Invectors provides contract services of drug delivery formulation developments to pharmaceutical/biotech industries and to public or private research centers.
Invectors services include formulation feasibility studies, process development and scale-up, formulation characterization, analytical and nonclinical services.
Formulation Development
- Specialized in the individuation of lipid-based drug delivery systems
- Labelling of the delivery system with bioactive peptides for selective targeting or for intracellular delivery
- Specialized in formulation of difficult compounds
- Formulation of small molecules, peptides/proteins, nucleic acids
- Solubility enhancement using liposomes and lipid-based systems
- Controlled/slow drug release systems
- Pre-formulation, formulation feasibility and prototype development
- Extrusion, homogenization, sonication and others
- Process development, scale-up and process optimization (Design-of-Experiments) and sterile grade filterability studies
Formulation Characterization
- Particle size
- Zeta Potential
- Particle size distribution
- Drug encapsulation efficiency
- Microscope examinations
- Particle shape, lamellarity and particle Sub-structure by TEM or cryo-TEM
- Phase transition, enthalpy of lipids and liposomes, protein denaturation temperatures
- Polymer glass transition, melting point
- Lyophylization/Freeze trying
Analytical Sciences
- HPLC method development
- HPLC measurement of drug potency
- Lipid concentration assay
- Formulation stability (chemical and physical)
- In vitro drug release assay
- Osmolality
- Refractive Index